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Increased Risk of Cognitive Impairment or Dementia in Women who Underwent Oophorectomy Before Menopause Neurol 69:1074-1083, Rocca,W.A.,et al, 2007 See this aricle in Pubmed Article Abstract Both unilateral and bilateral oophorectomy preceding the onset of menopause are associated with an increased risk of cognitive impairment or dementia. The effect is age-dependent and suggests a critical age window for neuroprotection.

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